Liverpool only shot in the direction of goal twice in the first leg, but scored both goals.
In the 75th minute, Firmino headed the ball at the near post and drove the ball to the far corner to score from Andy Robertson’s corner on the right wing.
The task of reaching the quarterfinals is even more difficult for Inter as they face a trip to Anfield in three weeks.
Roberto Firmino (left) celebrates the opening goal at host Inter’s stadium on the evening of February 16.
Goalkeeper Handanovic was defeated by Firmino’s dangerous header.
Jurgen Klopp became the first German coach to win 50 matches in the Champions League, with Dortmund and Liverpool.
Liverpool got into the game better with a good opportunity in the 14th minute, when Robertson hung the ball from a free kick for Mane to head over the bar from close range.
The two teams sequentially created opportunities, but the finishing quality was not high.
Liverpool lost midway through this period, but quickly regained the game thanks to Klopp’s three substitutions in the 59th minute. Luis Diaz, Jordan Henderson and Naby Keita entered the field and regained the game for the away team.
Inter 0-2 Liverpool
Most of Liverpool’s opportunities came from fixed situations, as well as two goals.
Liverpool will return to Anfield to play the next two matches in the Premier League against Norwich on February 19 and Leeds on February 23.
Competition list
Inter: Handanovic, Skriniar, de Vrij (Ranocchia 87), Bastoni (Dimarco 91), Dumfries (Darmian 87), Vidal (Gagliardini 87), Brozovic, Calhanoglu, Perisic, Martinez (Sanchez 70), Dzeko.
Liverpool: Alisson, Alexander-Arnold, Konate, van Dijk, Robertson, Thiago (Milner 86), Fabinho (Henderson 59), Elliott (Keita 59), Salah, Jota (Firmino 46), Mane (Diaz 59).